Phenotype Prediction: EU: 2194143; validated in UK, Germany, Switzerland, France, 29 June 2016. Inventors: Mark Vickers, Mark Hanson, Keith Godfrey, Cyrus Cooper, Peter Gluckman, Graham Burdge, Karen Lillycrop. Field of invention: The invention in general terms relates to the use of epigenetic markers in perinatal tissues as a means for predicting the propensity for the occurrence of a phenotype in an individual. In particular, for example, the invention relates to the prediction of a propensity for altered body composition, and altered bone mineral content occurring in an individual.
Predictive use of CpG methylation: EU: 2391730; validated in UK, Germany, Switzerland, France, 13 Apr 2016. Inventors: Allan Sheppard, Mark Hanson, Keith Godfrey, Cyrus Cooper, Peter Gluckman, Graham Burdge, Karen Lillycrop, Jo Slater-Jefferies. Field of invention: The present invention relates to use of epigenetic markers, more particularly methylation of one or more selected individual CpGs or CpG groups 5’ to the coding region of certain genes, especially in perinatal tissue such as umbilical cord, as a means of predicting diverse phenotypic characteristics in an individual in later life.
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