Science

Published Articles

Perspective: Human Milk Oligosaccharides: Fuel for Childhood Obesity Prevention?

Maessen, SE, Derraik, JGB, Binia, A, Cutfield, WS, Advances in Nutrition 2019 September 5. https://doi.org/10.1093/advances/nmz093

Relationships of maternal body mass index and plasma biomarkers with childhood body mass index and adiposity at 6 years

Dalrymple KV, Thompson JMD, Begum S, Godfrey KM, Poston L, Seed PT, McCowan LME, Wall C, Shelling A, North R, Cutfield WS, Mitchell EA, on behalf of the SCOPE Consortium: The Children of SCOPE study Pediatric Obesity 2019 June 24. https://doi.org/10.1111/ijpo.12537

Decomposing ethnic differences in body mass index and obesity rates among New Zealand pre-schoolers

Shackleton N, Derraik JGB, Audas R, Taylor RW, Marewa M, Morton SMB, Tautolo ES, Kokaua J, Taylor B, Cutfield WS, Milne BJ. International Journal of Obesity 2019 June 13.  [Epub ahead of print].  https://doi.org/10.1038/s41366-019-0390-4

Fracture prediction, imaging and screening in osteoporosis.

Fuggle NR, Curtis EM, Ward KA, Harvey NC, Dennison EM, Cooper C. Nature Reviews Endocrinology 2019 June 12.  https://doi.org/10.1038/s41574-019-0220-8

Cluster Analysis of Finite Element Analysis and Bone Microarchitectural Parameters Identifies Phenotypes with High Fracture Risk

Westbury LD, Shere C, Edwards MH, Cooper C, Dennison EM, Ward KA. Calcified Tissue International. 2019 June 11.  https://doi.org/10.1007/s00223-019-00564-7

Preterm Birth is Associated With Increased Blood Pressure in Young Adult Women

Skudder-Hill L, Ahlsson F, Lundgren M, Cutfield WS, Derraik JGB. Journal of the American Heart Association 2019 June 18.  Epub 2019 Jun 5. https://doi.org/10.1161/JAHA.119.012274

Altered vertebral and femoral bone structure in juvenile offspring of microswine subject to maternal low protein nutritional challenge.

Lanham SA, DuPriest E, Kupfer P, Cooper C, Bagby SP, Oreffo ROC. Physiological Reports 2019 June 7. (11):e14081. https://doi.org/10.14814/phy2.14081

Maternal sensitivity predicts anterior hippocampal functional networks in early childhood.

Wang, Q., Zhang, H., Wee, CY, Lee A, Poh JS, Chong YS, Tan KH, Gluckman PD, Yap F, Fortier MV, Rifkin-Graboi A, Qiu A. Brain Structure and Function (2019) 224: 1885. https://doi.org/10.1007/s00429-019-01882-0

Practical guidance for engaging patients in health research, treatment guidelines and regulatory processes: results of an expert group meeting organized by the World Health Organization (WHO) and the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO).

de Wit M, Cooper C, Tugwell P, Bere N, Kirwan J, Conaghan PG, Roberts C, Aujoulat I, Al-Daghri N, Araujo de Carvalho I, Barker M, Bedlington N, Brandi ML, Bruyère O, Burlet N, Halbout P, Hiligsmann M, Jiwa F, Kanis JA, Laslop A, Lawrence W, Pinto D, Prieto Yerro C, Rabenda V, Rizzoli R, Scholte-Voshaar M, Vlaskovska M, Reginster JY. Aging Clinical and Experimental Research. 2019 Jul;31(7):905-915. https://doi.org/10.1007/s40520-019-01193-8  Epub 2019 April 16.

Idiopathic short stature and growth hormone sensitivity in prepubertal children.

Derraik JGB, Miles HL, Chiavaroli V, Hofman PL, Cutfield WS. Clinical Endocrinology (Oxf). 2019 Jul;91(1):110-117. https://doi.org/10.1111/cen.13976  Epub 2019 Apr 10.

Impact of maternal body mass index and gestational weight gain on pregnancy complications: an individual participant data meta-analysis of European, North American and Australian cohorts.

Santos S, Voerman E, Amiano P, Barros H, Beilin LJ, Bergström A, Charles MA, Chatzi L, Chevrier C, Chrousos GP, Corpeleijn E, Costa O, Costet N, Crozier S, Devereux G, Doyon M, Eggesbø M, Fantini MP, Farchi S, Forastiere F, Georgiu V, Godfrey KM, Gori D, Grote V, Hanke W, Hertz-Picciotto I, Heude B, Hivert MF, Hryhorczuk D, Huang RC, Inskip H, Karvonen AM, Kenny LC, Koletzko B, Küpers LK, Lagström H, Lehmann I, Magnus P, Majewska R, Mäkelä J, Manios Y, McAuliffe FM, McDonald SW, Mehegan J, Melén E, Mommers M, Morgen CS, Moschonis G, Murray D, Ní Chaoimh C, Nohr EA, Nybo Andersen AM, Oken E, Oostvogels A, Pac A, Papadopoulou E, Pekkanen J, Pizzi C, Polanska K, Porta D, Richiardi L, Rifas-Shiman SL, Roeleveld N, Ronfani L, Santos AC, Standl M, Stigum H, Stoltenberg C, Thiering E, Thijs C, Torrent M, Tough SC, Trnovec T, Turner S, van Gelder M, van Rossem L, von Berg A, Vrijheid M, Vrijkotte T, West J, Wijga AH, Wright J, Zvinchuk O, Sørensen T, Lawlor DA, Gaillard R, Jaddoe V BJOG. 2019 Jul;126(8):984-995. https://doi.org/10.1111/1471-0528.15661  Epub 2019 Mar 20.

Epigenetic Age Acceleration in Adolescence Associates with BMI, Inflammation, and Risk Score for Middle Age Cardiovascular Disease.

Huang RC, Lillycrop KA, Beilin LJ, Godfrey KM, Anderson D, Mori TA, Rauschert S, Craig JM, Oddy WH, Ayonrinde OT, Pennell CE, Holbrook JD, Melton PE. The Journal of Clinical Endocrinology & Metabolism, Volume 104, Issue 7, 2019 July, Pages 3012–3024, https://doi.org/10.1210/jc.2018-02076

Changes in Stemness Properties, Differentiation Potential, Oxidative Stress, Senescence and Mitochondrial Function in Wharton’s Jelly Stem Cells of Umbilical Cords of Mothers with Gestational Diabetes Mellitus.Kong CM, Subramanian A, Biswas A, Stunkel W, Chong YS, Bongso A, Fong CY. Stem Cell Reviews and Reports (2019) 15: 415. https://doi.org/10.1007/s12015-019-9872-y

Nutritional Supplementation for the Prevention and/or Treatment of Gestational Diabetes Mellitus.

Plows JF, Reynolds CM, Vickers MH, Baker PN, Stanley JL. Current Diabetes Reports 2019 Aug 1;19(9):73. https://doi.org/10.1007/s11892-019-1199-1

Maternal undernutrition results in altered renal pro-inflammatory gene expression concomitant with hypertension in adult male offspring that is ameliorated following pre-weaning growth hormone treatmentZhang XD, Reynolds CM, Gray C, Li M, Vickers MH. J Dev Orig Health Dis. 2019 Aug;10(4):459-468. https://doi.org/10.1017/S2040174418000922

Sex-Dependent Associations among Maternal Depressive Symptoms, Child Reward Network, and Behaviors in Early Childhood.

Wang Q, Zhang H, Poh JS, Pecheva D, Broekman BFP, Chong YS, Shek LP, Gluckman PD, Fortier MV, Meaney MJ, Qiu A.   https://doi.org/10.1093/cercor/bhz135

Associations of maternal zinc and magnesium with offspring learning abilities and cognitive development at 4 years in GUSTO.

Lai JS, Cai S, Feng L, Shek LP, Yap F, Tan KH, Chong YS, Godfrey KM, Meaney MJ, Rifkin-Graboi A, Broekman BFP, Chong MFF. Nutritional Neuroscience. 2019 Jul 22:1-10. https://doi.org/10.1080/1028415X.2019.1643624  [Epub ahead of print]

Maternal feeding practices and children's food intake during an ad libitum buffet meal: Results from the GUSTO cohort.

Fries LR, Chan MJ, Quah PL, Toh JY, Fogel A, Goh AT, Aris IM, Broekman BFP, Cai S, Tint MT, Chong YS, Shek LP, Lee YS, Yap F, Tan KH, Gluckman PD, Godfrey KM, Silva Zolezzi I, Forde CG, Chong MFF. Appetite. 2019 Jul 16;142:104371. https://doi.org/10.1016/j.appet.2019.104371  [Epub ahead of print]

Cyclic glycine-proline administration normalizes high-fat diet-induced synaptophysin expression in obese rats.

Li F, Liu K, Wang A, Harris PWR, Vickers MH, Guan J. Neuropeptides. 2019 Aug;76. pii: S0143-4179(19)30019-8. https://doi.org/10.1016/j.npep.2019.05.006  Epub 2019 May 22.

Validation of a semi-quantitative FFQ for 18-month-old toddlers: the Growing Up in Singapore Towards Healthy Outcomes (GUSTO) study.

Lim HX, Toh JY, Tan KH, Chong YS, Yap F, Godfrey KM, Lee YS, Chong MF. Public Health Nutr. 2019 Aug;22(11):1990-2000.  https://doi.org/10.1017/S1368980019000557   Epub 2019 Apr 3.

High Maternal Circulating Cotinine During Pregnancy is Associated With Persistently Shorter Stature From Birth to Five Years in an Asian Cohort.

Ng S, Aris IM, Tint MT, Gluckman PD, Godfrey KM, Shek LP, Yap F, Tan KH, Lek N, Teoh OH, Chan YH, Chong MF, Lee YS, Chong YS, Kramer MS, Chan SY. Nicotine Tob Res. 2019 Jul 17;21(8):1103-1112. https://doi.org/10.1093/ntr/nty148

Preterm Birth: A Narrative Review of the Current Evidence on Nutritional and Bioactive Solutions for Risk Reduction.

Samuel TM, Sakwinska O, Makinen K, Burdge GC, Godfrey KM, Silva-Zolezzi I. Nutrients. 2019; 11(8):1811. https://doi.org/10.3390/nu11081811

Preconception health in England: a proposal for annual reporting with core metrics.

Stephenson J, Vogel C, Hall J, Hutchinson J, Mann S, Duncan H, Woods-Townsend K, de Lusignan S, Poston L, Cade J, Godfrey K, Hanson M, Barrett G, Barker M, Conti G, Shannon G, Colbourn T, The Lancet 2019; 393: 2262–71. Epub. June 1 2019. https://doi.org/10.1016/S0140-6736(19)30954-7

The case for including epigenetics in the school science curriculum and trainee science teachers’ views about its implications for society.

Grace M, Christodoulou A, Godfrey K, Hughes C, Griffiths J, Rietdijk W. School Science Review - in press. 2019 April 17.  URI: https://eprints.soton.ac.uk/id/eprint/431061

Neonatal amygdalae and hippocampi are influenced by genotype and prenatal environment, and reflected in the neonatal DNA methylome.  

Ong ML, Anh Tuan T, Poh J, Teh AL, Chen L, Pan H, MacIsaac JL, Kobor MS, Chong YS, Kwek K, Saw SM, Godfrey KM, Gluckman PD, Fortier MV, Karnani N, Meaney MJ, Qiu A, Holbrook JD. Genes Brain Behav 2019:e12576. Epub Apr 24.   https://doi.org/10.1111/gbb.12576

Relationships of maternal body mass index and plasma biomarkers with childhood body mass index and adiposity at 6 years; the Children of SCOPE study

Begum S, Thompson JMD, Dalrymple KV, Godfrey KM, Poston L, Seed PT, McCowan LME, Wall C, Shelling A, North R, Huang Y, Cutfield WS, Mitchell EA, SCOPE Consortium.. Pediatr Obesity – in press. 2019 June 24. https://onlinelibrary.wiley.com/doi/full/10.1111/ijpo.12537

Validation of the Children's Eating Behavior Questionnaire in 5 and 6 Year-Old Children: The GUSTO Cohort Study.  

Quah PL, Fries LR, Chan MJ, Fogel A, McCrickerd K, Goh AT, Aris IM, Lee YS, Pang WW, Basnyat I, Wee HL, Yap F, Godfrey KM, Chong YS, Shek LPC, Tan KH, Forde CG, Chong MFF. Front Psychol 2019;10:824. Epub. 2019 11 April   https://www.frontiersin.org/articles/10.3389/fpsyg.2019.00824/full

Associations between inhibitory control, eating behaviours and adiposity in 6-year-old children.

Fogel A, McCrickerd K, Goh AT, Fries LR, Chong YS, Tan KH, Yap F, Shek LP, Meaney MJ, Cai S, Silveira PP, Broekman BFP, Lee YS, Godfrey KM, Chong MFF, Forde CG. Int J Obes 2019 – in press. Epub. 2019 Mar 28. https://www.nature.com/articles/s41366-019-0343-y

Maternal plasma vitamin B12 concentrations during pregnancy and infant cognitive outcomes at 2 years of age.  

Lai JS, Mohamad Ayob MN, Cai S, Quah PL, Gluckman PD, Shek LP, Yap F, Tan KH, Chong YS, Godfrey KM, Meaney MJ, Broekman BFP, Rifkin-Graboi A, Chong MFF. Br J Nutr 2019 – in press. Epub Apr 2:1-26.  DOI: https://doi.org/10.1017/S0007114519000746

Longitudinal Analysis Between Maternal Feeding Practices and Body Mass Index (BMI): A Study in Asian Singaporean Preschoolers.

Quah PL, Ng JC, Fries LR, Chan MJ, Aris IM, Lee YS, Yap F, Godfrey KM, Chong YS, Shek LP, Tan KH, Forde CG, Chong MFF. Front Nutr. 2019 Epub 2019 April 2; 6:32.  https://www.frontiersin.org/articles/10.3389/fnut.2019.00032/full

Iron status and risk factors of iron deficiency among pregnant women in Singapore: a cross-sectional study.

Loy SL, Lim LM, Chan SY, Tan PT, Chee YL, Quah PL, Chan JKY, Tan KH, Yap F, Godfrey KM, Shek LP, Chong MF, Kramer MS, Chong YS, Chi C. BMC Public Health. 2019 Epub Apr 11;19(1):397. https://bmcpublichealth.biomedcentral.com/articles/10.1186/s12889-019-6…

Sex-specific longitudinal associations of screen viewing time in children at 2-3 years with adiposity at 3-5 years.

Padmapriya N, Aris IM, Tint MT, Loy SL, Cai S, Tan KH, Shek LP, Chong YS, Godfrey KM, Gluckman PD, Lee YS, Saw SM, Yap F, Kramer MS, Bernard JY, Müller-Riemenschneider F. Int J Obes (Lond). Epub 2019 April 2. https://www.ncbi.nlm.nih.gov/pubmed/30940915

Validation of a semi-quantitative FFQ for 18-month-old toddlers: the Growing Up in Singapore Towards Healthy Outcomes (GUSTO) study.

Lim HX, Toh JY, Tan KH, Chong YS, Yap F, Godfrey KM, Lee YS, Chong MF. Public Health Nutr. 2019 Epub Apr 3:1-11.  https://www.cambridge.org/core/journals/public-health-nutrition/article…

Functional Urate-Associated Genetic Variants Influence Expression of lincRNAs LINC01229 and MAFTRR

Leask M, Dowdle A, Salvesen H, Topless R, Fadason T, Wei W, Schierding W, Marsman J, Antony J, O'Sullivan JM, Merriman TR, Horsfield JA. Corrigendum: Front Genet. 2019 Epub Apr 24;10:382. https://www.frontiersin.org/articles/10.3389/fgene.2018.00733/full

Minimal clinically important decline in physical function over one year:

Siviero P, Limongi F, Gesmundo A, Zambon S, Cooper C, Dennison EM, Edwards MH, Timmermans EJ, van der Pas S, Schaap LA, van Schoor NM, Denkinger MD, Herbolsheimer F, Peter R, Castell MV, Otero Á, Queipo R, Pedersen NL, Deeg DJH, Maggi S; EPOSA Research Group. EPOSA study BMC Musculoskelet Disord. 2019 Epub May 17;20(1):227 https://bmcmusculoskeletdisord.biomedcentral.com/articles/10.1186/s12891-019-2593-1

Vitamin D, and Maternal and Child Health

Moon RJ, Davies JH, Cooper C, Harvey NC. Calcif Tissue Int. Epub. 2019 May 14. https://link.springer.com/article/10.1007/s00223-019-00560-x

Prenatal influences on bone health in children

Woolford SJ, Cooper C, Harvey N, Moon RJ.. Expert Rev Endocrinol Metab. 2019 Epub May;14(3):193-202 https://www.tandfonline.com/doi/full/10.1080/17446651.2019.1607727

Associations of physical activity levels and screen time with oral glucose tolerance test profiles in Singaporean women of reproductive age actively trying to conceive

Bernard JY, Ng S, Natarajan P, Loy SL, Aris IM, Tint MT, Chong YS, Shek L, Chan J, Godfrey KM, Khoo CM, Leow MK, Müller-Riemenschneider F, Chan SY.: the S-PRESTO study. Diabet Med. 2019 Epub Mar 19.  https://www.ncbi.nlm.nih.gov/pubmed/30888073

Vitamin D supplementation for musculoskeletal health outcomes in adults - The end of the beginning?

Abrahamsen B, Harvey NC. Maturitas. 2019 Epub  Apr;122:87-88.    https://www.ncbi.nlm.nih.gov/pubmed/30401588

Maternal plasma vitamin B12 concentrations during pregnancy and infant cognitive outcomes at 2 years of age.

Lai JS, Mohamad Ayob MN, Cai S, Quah PL, Gluckman PD, Shek LP, Yap F, Tan KH, Chong YS, Godfrey KM, Meaney MJ, Broekman BFP, Rifkin-Graboi A, Chong MFF. Br J Nutr. 2019 Epub Apr 2:1-26. DOI: https://doi.org/10.1017/S0007114519000746

Gut microbiota and osteoarthritis management: an expert consensus of the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO).

Biver E, Berenbaum F, Valdes AM, de Carvalho IA, Bindels LB, Brandi ML, Calder PC, Castronovo V, Cavalier E, Cherubini A, Cooper C, Dennison E, Franceschi C, Fuggle N, Laslop A, Miossec P, Thomas T, Tuzun S, Veronese N, Vlaskovska M, Reginster JY, Rizzoli R. Ageing Res Rev. 2019 Aug 19:100946. doi: 10.1016/j.arr.2019.100946. [Epub ahead of print]

Television viewing and child cognition in a longitudinal birth cohort in Singapore: the role of maternal factors.

Aishworiya R, Cai S, Chen HY, Phua DY, Broekman BFP, Daniel LM, Chong YS, Shek LP, Yap F, Chan SY, Meaney MJ, Law EC. BMC Pediatr. 2019 Aug 16;19:286. doi: 10.1186/s12887-019-1651-z. PubMed Central PMCID: PMC6696668.

Differential SLC6A4 methylation: a predictive epigenetic marker of adiposity from birth to adulthood

Karen A. Lillycrop, Emma S. Garratt, Philip Titcombe, Phillip E. Melton, Robert J. S. Murray, Sheila J. Barton, Rebecca Clarke-Harris, Paula M. Costello,  Joanna D. Holbrook, James C. Hopkins, Caroline E. Childs, Carolina Paras-Chavez, Philip C. Calder, Trevor A. Mori, Lawrie Beilin, Graham C. Burdge, Peter D. Gluckman, Hazel M. Inskip, Nicholas C. Harvey, Mark A. Hanson, Rae-Chi Huang, Cyrus Cooper, EpiGen Consortium & Keith M. Godfrey International Journal of Obesity  2019 Jan 8. https://doi.org/10.1038/s41366-018-0254-3

Association between maternal mid-gestation vitamin D status and neonatal abdominal adiposity.

Mya Thway Tint, Mary F Chong, Izzuddin M Aris, Keith M Godfrey, Phaik Ling Quah, Jeevesh Kapur, Seang Mei Saw, Peter D Gluckman, Victor S. Rajadurai, Fabian Yap, Michael S Kramer, Yap-Seng Chong, Christiani Jeyakumar Henry, Marielle V Fortier & Yung Seng Lee. Int J Obes (Lond). 2018 Mar 9. https://doi.org/10.1038/s41366-018-0032-2

FUT2 gene variants and reported respiratory and gastrointestinal illnesses during infancy.

Barton SJ, Murray R, Lillycrop KA, Inskip HM, Harvey NC, Cooper C, Karnani N, Silva Zolezzi I, Sprenger N, Godfrey KM, Binia A. J Infectious Dis 2018 – in press. Epub Oct 30. https://doi.org/10.1093/infdis/jiy582

Maternal plasma phosphatidylcholine polyunsaturated fatty acids during pregnancy and offspring growth and adiposity, Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA)

Jonathan Y. Bernard, Mya-Thway Tint, Izzuddin M. Aris, Ling-Wei Chen, Phaik Ling Quah, Kok Hian Tan, George Seow-Heong Yeo, Marielle V. Fortier, Fabian Yap, Lynette Shek, Yap-Seng Chong, Peter D. Gluckman, Keith M. Godfrey, Philip C. Calder, Mary F.F. Chong, Michael S. Kramer, Jérémie Botton, Yung Seng Lee

Volume 121, 2017 June, Pages 21-29, ISSN 0952-3278, https://doi.org/10.1016/j.plefa.2017.05.006

ANRIL Promoter DNA Methylation: A Perinatal Marker for Later Adiposity

Karen Lillycrop1, Robert Murray, Clara Cheong, Ai Ling Teh, Rebecca Clarke-Harris, Sheila Barton, Paula Costello, Emma Garratt, Eloise Cook, Philip Titcombe, Bhuvaneshwari Shunmuganathan, Samantha J. Liew, Yong-Cai Chua, Xinyi Lin, Yonghui Wu, Graham C. Burdge, Cyrus Cooper, Hazel M. Inskip, Neerja Karnani, James C. Hopkins, Caroline E. Childs, Carolina Paras Chavez, Philip C. Calder, Fabian Yap, Yung Seng Lee, Yap Seng Chong, Philip E. Melton, Lawrie Beilin, Rae-Chi Huang, Peter D. Gluckman, Nick Harvey, Mark A. Hanson, Joanna D. Holbrook, The EpiGen Consortium, Keith M. Godfrey

EBioMedicine 2017 Apr 26. DOI: http://dx.doi.org/10.1016/j.ebiom.2017.03.037 

Perinatal DNA methylation at CDKN2A is associated with offspring bone mass: Findings from the Southampton Women's Survey.

Curtis EM, Murray R, Titcombe P, Cook E, Clarke-Harris R, Costello P, Garratt E, Holbrook JD, Barton S, Inskip H, Godfrey KM, Bell CG, Cooper C, Lillycrop KA, Harvey NC.

J Bone Miner Res

2017 Apr 17.  doi: 10.1002/jbmr.3153. Epub 2017 May 22.

The Effects of Myo-Inositol and B and D Vitamin Supplementation in the db/+ Mouse Model of Gestational Diabetes Mellitus.

Plows JF, Budin F, Andersson RA, Mills VJ, Mace K, Davidge ST, Vickers MH, Baker PN, Silva-Zolezzi I, Stanley JL.  Nutrients. 2017 Feb 15;9(2). pii: E141. doi: 10.3390/nu9020141.

A description of the ‘obesogenic’ eating style that promotes energy intake in 4.5 year-old children: Results from the GUSTO cohort.

Fogel A, Goh AT, Fries LR, Sadananthan SA, Velan SS, Michael N, Tint MT, Fortier MV, Chan MJ, Toh JY, Chong YS, Tan KH, Yap F, Shek LP, Meaney MJ, Broekman BF, Lee YS, Godfrey KM, Chong MF, Forde CG.  Physiol Behav. 2017 Feb 14. pii: S0031-9384(16)31158-1. doi: 10.1016/j.physbeh.2017.02.013.

Does the maternal vaginal microbiota play a role in seeding the microbiota of neonatal gut and nose?

Sakwinska O, Foata F, Berger B, Brüssow H, Combremont S, Mercenier A, Dogra S, Soh SE, Yen JCK, Heong GYS, Lee YS, Yap F, Meaney MJ, Chong YS, Godfrey KM, Holbrook JD. Benef Microbes. 2017; 8: 763-778.

Catching diabetes

Holbrook JD.

Epigenomics 2016;8(9):1173-77 doi: 10.2217/epi-2016-0079 published Online First: Epub 2016 Sep.

PMID: 27529737

 

DNA methylation at birth within the promoter of ANRIL predicts markers of cardiovascular risk at 9 years.

Murray R, Bryant J, Titcombe P, Barton SJ, Inskip H, Harvey NC, Cooper C, Lillycrop K, Hanson M, Godfrey KM.

Clin Epigenetics. 2016 Sep 2;8:90. doi: 10.1186/s13148-016-0259-5. eCollection 2016.

PMID: 27594927 [PubMed - in process] Free PMC Article

 

The association of maternal vitamin D status with infant birth outcomes, postnatal growth and adiposity in the first 2 years of life in a multi-ethnic Asian population: the Growing Up in Singapore Towards healthy Outcomes (GUSTO) cohort study.

Ong YL, Quah PL, Tint MT, Aris IM, Chen LW, van Dam RM, Heppe D, Saw SM, Godfrey KM, Gluckman PD, Chong YS, Yap F, Lee YS, Foong-Fong Chong M.

Br J Nutr. 2016 Aug;116(4):621-31. doi: 10.1017/S0007114516000623. Epub 2016 Jun 24.

 

Sexually dimorphic response to feeding mode in the growth of infants.

Cheng TS, Loy SL, Cheung YB, Chan JK, Pang WW, Godfrey KM, Gluckman PD, Kwek K, Saw SM, Chong YS, Lee YS, Lek N, Yap F.

Am J Clin Nutr. 2016 Feb;103(2):398-405. doi: 10.3945/ajcn.115.115493. Epub 2015 Dec 30.

PMID: 26718413 [PubMed - indexed for MEDLINE]

 

Dynamics of infant gut microbiota are influenced by delivery mode and gestational duration and are associated with subsequent adiposity.

Dogra S, Sakwinska O, Soh SE, Ngom-Bru C, Brück WM, Berger B, Brüssow H, Lee YS, Yap F, Chong YS, Godfrey KM, Holbrook JD; GUSTO Study Group.

MBio. 2015 Feb 3;6(1). pii: e02419-14. doi: 10.1128/mBio.02419-14.

PMID: 25650398 [PubMed - indexed for MEDLINE] Free PMC Article

 

Rate of establishing the gut microbiota in infancy has consequences for future health.

Dogra S, Sakwinska O, Soh SE, Ngom-Bru C, Brück WM, Berger B, Brüssow H, Karnani N, Lee YS, Yap F, Chong YS, Godfrey KM, Holbrook JD.

Gut Microbes. 2015;6(5):321-5. doi: 10.1080/19490976.2015.1078051. Epub 2015 Aug 20.

PMID: 26516657 [PubMed - indexed for MEDLINE] Free PMC Article

 

Genome-wide methylation analysis identifies differentially methylated CpG loci associated with severe obesity in childhood.

Huang RC, Garratt ES, Pan H, Wu Y, Davis EA, Barton SJ, Burdge GC, Godfrey KM, Holbrook JD, Lillycrop KA.

Epigenetics. 2015;10(11):995-1005. doi: 10.1080/15592294.2015.1080411.

PMID: 26646899 [PubMed - in process] Free PMC Article

 

Long-chain polyunsaturated fatty acid status during pregnancy and maternal mental health in pregnancy and the postpartum period: results from the GUSTO study.

Chong MF, Ong YL, Calder PC, Colega M, Wong JX, Tan CS, Lim AL, Fisk HL, Cai S, Pang WW, Broekman BF, Saw SM, Kwek K, Godfrey KM, Chong YS, Gluckman P, Meaney MJ, Chen H; GUSTO Study Group.

J Clin Psychiatry. 2015 Jul;76(7):e848-56. doi: 10.4088/JCP.14m09191.

PMID: 26231011 [PubMed - indexed for MEDLINE]

 

HIF3A association with adiposity: the story begins before birth.

Pan H, Lin X, Wu Y, Chen L, Teh AL, Soh SE, Lee YS, Tint MT, MacIsaac JL, Morin AM, Tan KH, Yap F, Saw SM, Kobor MS, Meaney MJ, Godfrey KM, Chong YS, Gluckman PD, Karnani N, Holbrook JD; GUSTO Study Group.

Epigenomics. 2015;7(6):937-50. doi: 10.2217/epi.15.45. Epub 2015 May 26.

PMID: 26011824 [PubMed - indexed for MEDLINE] Free PMC Article

 

Maternal Protein Intake during Pregnancy Is Not Associated with Offspring Birth Weight in a Multiethnic Asian Population.

Chong MF, Chia AR, Colega M, Tint MT, Aris IM, Chong YS, Gluckman P, Godfrey KM, Kwek K, Saw SM, Yap F, van Dam RM, Lee YS; GUSTO Study Group.

J Nutr. 2015 Jun;145(6):1303-10. doi: 10.3945/jn.114.205948. Epub 2015 May 6.

PMID: 25948786 [PubMed - indexed for MEDLINE] Free Article

 

Association between perinatal methylation of the neuronal differentiation regulator HES1 and later childhood neurocognitive function and behaviour.

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